Jan Hasenauer: search on Z-Library

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1

Inferring population dynamics from single-cell RNA-sequencing time series data

Fischer, David S., Fiedler, Anna K., Kernfeld, Eric M., Genga, Ryan M. J., Bastidas-Ponce, Aimée, Bakhti, Mostafa, Lickert, Heiko, Hasenauer, Jan, Maehr, Rene, Theis, Fabian J.

Journal:

Nature Biotechnology

Year:

2019

Language:

english

File:

PDF, 13.79 MB

english, 2019

2

Model-based analysis of response and resistance factors of cetuximab treatment in gastric cancer cell lines

RaimÃºndez, Elba, Keller, Simone, Ebert, Karolin, Hug, Sabine, Theis, Fabian J., Maier, Dieter, Luber, Birgit, Hasenauer, Jan, Gallo, James

Journal:

PLoS Computational Biology

Year:

2020

File:

PDF, 4.93 MB

2020

3

PKA-RII subunit phosphorylation precedes activation by cAMP and regulates activity termination

Isensee, Jörg, Kaufholz, Melanie, Knape, Matthias J., Hasenauer, Jan, Hammerich, Hanna, Gonczarowska-Jorge, Humberto, Zahedi, René P., Schwede, Frank, Herberg, Friedrich W., Hucho, Tim

Journal:

The Journal of Cell Biology

Year:

2018

Language:

english

File:

PDF, 3.41 MB

english, 2018

4

Dynamical optimization using reduced order models: A method to guarantee performance

Jan Hasenauer, Martin Löhning, Mustafa Khammash, Frank Allgöwer

Journal:

Journal of Process Control

Year:

2012

Language:

english

File:

PDF, 904 KB

english, 2012

5

Whither systems medicine?

Apweiler, Rolf, Beissbarth, Tim, Berthold, Michael R, Blüthgen, Nils, Burmeister, Yvonne, Dammann, Olaf, Deutsch, Andreas, Feuerhake, Friedrich, Franke, Andre, Hasenauer, Jan, Hoffmann, Steve, Höfer,

Journal:

Experimental and Molecular Medicine

Year:

2018

Language:

english

File:

PDF, 502 KB

english, 2018

6

Robust calibration of hierarchical population models for heterogeneous cell populations

Loos, Carolin, Hasenauer, Jan

Journal:

Journal of Theoretical Biology

Year:

2020

Language:

english

File:

PDF, 2.18 MB

english, 2020

7

Identification of models of heterogeneous cell populations from population snapshot data

Jan Hasenauer, Steffen Waldherr, Malgorzata Doszczak, Nicole Radde, Peter Scheurich, Frank Allgöwer

Journal:

BMC Bioinformatics

Year:

2011

Language:

english

File:

PDF, 2.16 MB

english, 2011

8

Model predictive control using reduced order models: Guaranteed stability for constrained linear systems

Löhning, Martin, Reble, Marcus, Hasenauer, Jan, Yu, Shuyou, Allgöwer, Frank

Journal:

Journal of Process Control

Year:

2014

Language:

english

File:

PDF, 1.40 MB

english, 2014

9

Efficient parameterization of large-scale dynamic models based on relative measurements

Schmiester, Leonard, Schälte, Yannik, Fröhlich, Fabian, Hasenauer, Jan, Weindl, Daniel, Schwartz, Russell

Journal:

Year:

2019

Language:

english

File:

PDF, 639 KB

english, 2019

10

Analysis of heterogeneous cell populations: A density-based modeling and identification framework

Jan Hasenauer, Steffen Waldherr, Malgorzata Doszczak, Peter Scheurich, Nicole Radde, Frank Allgöwer

Journal:

Journal of Process Control

Year:

2011

Language:

english

File:

PDF, 522 KB

english, 2011

11

Estimation of biochemical network parameter distributions in cell populations

Waldherr, Steffen, Hasenauer, Jan, Allgöwer, Frank

Journal:

IFAC Proceedings Volumes

Year:

2009

Language:

english

File:

PDF, 327 KB

english, 2009

12

An adaptive scheduling scheme for calculating Bayes factors with thermodynamic integration using Simpson’s rule

Hug, Sabine, Schwarzfischer, Michael, Hasenauer, Jan, Marr, Carsten, Theis, Fabian J.

Journal:

Statistics and Computing

Year:

2016

Language:

english

File:

PDF, 683 KB

english, 2016

13

Benchmarking optimization methods for parameter estimation in large kinetic models

Villaverde, Alejandro F, Fröhlich, Fabian, Weindl, Daniel, Hasenauer, Jan, Banga, Julio R, Stegle, Oliver

Journal:

Year:

2018

Language:

english

File:

PDF, 1.40 MB

english, 2018

14

Closing the gap between formats for storing layout information in systems biology

Hoksza, David, Gawron, Piotr, Ostaszewski, Marek, Hasenauer, Jan, Schneider, Reinhard

Journal:

Briefings in Bioinformatics

Year:

2020

File:

PDF, 92 KB

2020

15

[IEEE 2012 IEEE Symposium on Biological Data Visualization (BioVis) - Seattle, WA, USA (2012.10.14-2012.10.15)] 2012 IEEE Symposium on Biological Data Visualization (BioVis) - Uncertainty-aware visual analysis of biochemical reaction networks

Vehlow, Corinna, Hasenauer, Jan, Kramer, Andrei, Heinrich, Julian, Radde, Nicole, Allgower, Frank, Weiskopf, Daniel

Year:

2012

Language:

english

File:

PDF, 1.32 MB

english, 2012

16

pyABC: distributed, likelihood-free inference

Klinger, Emmanuel, Rickert, Dennis, Hasenauer, Jan, Stegle, Oliver

Journal:

Year:

2018

Language:

english

File:

PDF, 100 KB

english, 2018

17

Dirac mixture distributions for the approximation of mixed effects models

Wang, Dantong, Stapor, Paul, Hasenauer, Jan

Journal:

IFAC-PapersOnLine

Year:

2019

File:

PDF, 1.40 MB

2019

18

A visual analytics approach for models of heterogeneous cell populations

Hasenauer, Jan, Heinrich, Julian, Doszczak, Malgorzata, Scheurich, Peter, Weiskopf, Daniel, Allgöwer, Frank

Journal:

EURASIP Journal on Bioinformatics and Systems Biology

Year:

2012

Language:

english

File:

PDF, 414 KB

english, 2012

19

Parameter estimation for dynamical systems with discrete events and logical operations

Fröhlich, Fabian, Theis, Fabian J., Rädler, Joachim O., Hasenauer, Jan

Journal:

Year:

2016

Language:

english

File:

PDF, 606 KB

english, 2016

20

Threshold-Free Population Analysis Identifies Larger DRG Neurons to Respond Stronger to NGF Stimulation

Andres, Christine, Hasenauer, Jan, Allgower, Frank, Hucho, Tim, Obukhov, Alexander G.

Journal:

Year:

2012

Language:

english

File:

PDF, 584 KB

english, 2012

21

Mathematical modeling of variability in intracellular signaling

Loos, Carolin, Hasenauer, Jan

Journal:

Current Opinion in Systems Biology

Year:

2019

File:

PDF, 1.08 MB

2019

22

Analysis of CFSE time-series data using division-, age- and label-structured population models

Hross, Sabrina, Hasenauer, Jan

Journal:

Year:

2016

File:

PDF, 853 KB

2016

23

Fluorescence optical imaging and 3T-MRI for detection of synovitis in patients with rheumatoid arthritis in comparison to a composite standard of reference

Thuermel, Klaus, Neumann, Jan, Jungmann, Pia M., Schäffeler, Christoph, Waldt, Simone, Heinze, Alexander, Beckmann, Alexander, Hauser, Christine, Hasenau, Anna-Lena, Wildgruber, Moritz, Clotten, Sigru

Journal:

European Journal of Radiology

Year:

2017

Language:

english

File:

PDF, 659 KB

english, 2017

24

A scalable moment-closure approximation for large-scale biochemical reaction networks

Kazeroonian, Atefeh, Theis, Fabian J, Hasenauer, Jan

Journal:

Year:

2017

Language:

english

File:

PDF, 1.84 MB

english, 2017

25

ODE Constrained Mixture Modelling: A Method for Unraveling Subpopulation Structures and Dynamics

Hasenauer, Jan, Hasenauer, Christine, Hucho, Tim, Theis, Fabian J., Stelling, Jorg

Journal:

PLoS Computational Biology

Year:

2014

Language:

english

File:

PDF, 1.82 MB

english, 2014

26

Effects of trastuzumab and afatinib on kinase activity in gastric cancer cell lines

Keller, Simone, Zwingenberger, Gwen, Ebert, Karolin, Hasenauer, Jan, Wasmuth, Jacqueline, Maier, Dieter, Haffner, Ivonne, Schierle, Katrin, Weirich, Gregor, Luber, Birgit

Journal:

Molecular Oncology

Year:

2018

Language:

english

File:

PDF, 825 KB

english, 2018

27

Increasing Neural Stem Cell Division Asymmetry and Quiescence Are Predicted to Contribute to the Age-Related Decline in Neurogenesis

Bast, Lisa, Calzolari, Filippo, Strasser, Michael K., Hasenauer, Jan, Theis, Fabian J., Ninkovic, Jovica, Marr, Carsten

Journal:

Year:

2018

Language:

english

File:

PDF, 5.53 MB

english, 2018

28

Trajectory-based model reduction of nonlinear biochemical networks employing the observability normal form*

Löhning, Martin, Hasenauer, Jan, Allgöwer, Frank

Journal:

IFAC Proceedings Volumes

Year:

2011

Language:

english

File:

PDF, 528 KB

english, 2011

29

Multi-experiment nonlinear mixed effect modeling of single-cell translation kinetics after transfection

Fröhlich, Fabian, Reiser, Anita, Fink, Laura, Woschée, Daniel, Ligon, Thomas, Theis, Fabian Joachim, Rädler, Joachim Oskar, Hasenauer, Jan

Journal:

npj Systems Biology and Applications

Year:

2019

Language:

english

File:

PDF, 2.08 MB

english, 2019

30

Efficient computation of steady states in large-scale ODE models of biochemical reaction networks

Terje Lines, Glenn, Paszkowski, Łukasz, Schmiester, Leonard, Weindl, Daniel, Stapor, Paul, Hasenauer, Jan

Journal:

IFAC-PapersOnLine

Year:

2019

File:

PDF, 464 KB

2019

31

GenSSI 2.0: multi-experiment structural identifiability analysis of SBML models

Ligon, Thomas S, Fröhlich, Fabian, Chiş, Oana T, Banga, Julio R, Balsa-Canto, Eva, Hasenauer, Jan

Journal:

Year:

2017

Language:

english

File:

PDF, 155 KB

english, 2017

32

Correction to: Determining the effects of trastuzumab, cetuximab and afatinib by phosphoprotein, gene expression and phenotypic analysis in gastric cancer cell lines

Ebert, Karolin, Zwingenberger, Gwen, Barbaria, Elena, Keller, Simone, Heck, Corinna, Arnold, Rouven, Hollerieth, Vanessa, Mattes, Julian, Geffers, Robert, RaimÃºndez, Elba, Hasenauer, Jan, Luber, Birg

Journal:

Year:

2020

File:

PDF, 202 KB

2020

33

Dominant Negative Effects of Tumor Necrosis Factor (TNF)-related Apoptosis-inducing Ligand (TRAIL) Receptor 4 on TRAIL Receptor 1 Signaling by Formation of Heteromeric Complexes

Neumann, Simon, Hasenauer, Jan, Pollak, Nadine, Scheurich, Peter

Journal:

Journal of Biological Chemistry

Year:

2014

Language:

english

File:

PDF, 2.37 MB

english, 2014

34

[IEEE 2011 50th IEEE Conference on Decision and Control and European Control Conference (CDC-ECC 2011) - Orlando, FL, USA (2011.12.12-2011.12.15)] IEEE Conference on Decision and Control and European Control Conference - Steady state stability preserving nonlinear model reduction using sequential convex optimization

Lohning, Martin, Hasenauer, Jan, Allgower, Frank

Year:

2011

Language:

english

File:

PDF, 209 KB

english, 2011

35

CERENA: ChEmical REaction Network Analyzer—A Toolbox for the Simulation and Analysis of Stochastic Chemical Kinetics

Kazeroonian, Atefeh, Fröhlich, Fabian, Raue, Andreas, Theis, Fabian J., Hasenauer, Jan, Salahub, Dennis

Journal:

Year:

2016

Language:

english

File:

PDF, 2.50 MB

english, 2016

36

A Comparison of Methods for Quantifying Prediction Uncertainty in Systems Biology

Villaverde, Alejandro F., Raimúndez, Elba, Hasenauer, Jan, Banga, Julio R.

Journal:

IFAC-PapersOnLine

Year:

2019

File:

PDF, 3.36 MB

2019

37

PESTO: Parameter EStimation TOolbox

Stapor, Paul, Weindl, Daniel, Ballnus, Benjamin, Hug, Sabine, Loos, Carolin, Fiedler, Anna, Krause, Sabrina, Hroß, Sabrina, Fröhlich, Fabian, Hasenauer, Jan

Journal:

Year:

2017

Language:

english

File:

PDF, 116 KB

english, 2017

38

Mathematical modeling of variability in intracellular signaling

Loos, Carolin, Hasenauer, Jan

Journal:

Current Opinion in Systems Biology

Year:

2019

Language:

english

File:

PDF, 1.08 MB

english, 2019

39

Parameterization of mechanistic models from qualitative data using an efficient optimal scaling approach

Schmiester, Leonard, Weindl, Daniel, Hasenauer, Jan

Journal:

Journal of Mathematical Biology

Year:

2020

File:

PDF, 1.12 MB

2020

40

Sharpening of expression domains induced by transcription and microRNA regulation within a spatio-temporal model of mid-hindbrain boundary formation

Sabrina Hock, Yen-Kar Ng, Jan Hasenauer, Dominik Wittmann…

Journal:

BMC Systems Biology

Year:

2013

Language:

english

File:

PDF, 805 KB

english, 2013

41

Wound-healing growth factor, basic FGF, induces Erk1/2-dependent mechanical hyperalgesia

Andres, Christine, Hasenauer, Jan, Ahn, Hye-Sook, Joseph, Elizabeth K., Isensee, Jörg, Theis, Fabian J., Allgöwer, Frank, Levine, Jon D., Dib-Hajj, Sulayman D., Waxman, Stephen G., Hucho, Tim

Journal:

Year:

2013

Language:

english

File:

PDF, 1.43 MB

english, 2013

42

Robust parameter estimation for dynamical systems from outlier-corrupted data

Maier, Corinna, Loos, Carolin, Hasenauer, Jan

Journal:

Year:

2017

Language:

english

File:

PDF, 913 KB

english, 2017

43

Evaluation of Derivative-Free Optimizers for Parameter Estimation in Systems Biology

Schälte, Yannik, Stapor, Paul, Hasenauer, Jan

Journal:

IFAC-PapersOnLine

Year:

2018

Language:

english

File:

PDF, 489 KB

english, 2018

44

Challenges in the calibration of large-scale ordinary differential equation models

Kapfer, Eva-Maria, Stapor, Paul, Hasenauer, Jan

Journal:

IFAC-PapersOnLine

Year:

2019

File:

PDF, 573 KB

2019

45

Determinants of robustness in spindle assembly checkpoint signalling

Heinrich, Stephanie, Geissen, Eva-Maria, Kamenz, Julia, Trautmann, Susanne, Widmer, Christian, Drewe, Philipp, Knop, Michael, Radde, Nicole, Hasenauer, Jan, Hauf, Silke

Journal:

Nature Cell Biology

Year:

2013

Language:

english

File:

PDF, 8.27 MB

english, 2013

46

[IEEE 2010 49th IEEE Conference on Decision and Control (CDC) - Atlanta, GA, USA (2010.12.15-2010.12.17)] 49th IEEE Conference on Decision and Control (CDC) - Approximative classification of regions in parameter spaces of nonlinear ODEs yielding different qualitative behavior

Hasenauer, Jan, Breindl, Christian, Waldherr, Steffen, Allgower, Frank

Year:

2010

Language:

english

File:

PDF, 460 KB

english, 2010

47

Analysis of CFSE time-series data using division-, age- and label-structured population models

Hross, Sabrina, Hasenauer, Jan

Journal:

Year:

2016

Language:

english

File:

PDF, 853 KB

english, 2016

48

Guaranteed Steady-State Bounds for Uncertain Chemical Processes

Hasenauer, Jan, Rumschinski, Philipp, Waldherr, Steffen, Borchers, Steffen, Allgöwer, Frank, Findeisen, Rolf

Journal:

IFAC Proceedings Volumes

Year:

2009

Language:

english

File:

PDF, 222 KB

english, 2009

49

A Hierarchical, Data-Driven Approach to Modeling Single-Cell Populations Predicts Latent Causes of Cell-To-Cell Variability

Loos, Carolin, Moeller, Katharina, Fröhlich, Fabian, Hucho, Tim, Hasenauer, Jan

Journal:

Year:

2018

Language:

english

File:

PDF, 13.70 MB

english, 2018

50

Efficient exact inference for dynamical systems with noisy measurements using sequential approximate Bayesian computation

SchÃ¤lte, Yannik, Hasenauer, Jan

Journal:

Year:

2020

File:

PDF, 644 KB

2020

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